Dasatinib相关论文
Electrochemical sensing for Caspase-3 activity from dasatinib-induced apoptosis using functionalized
Dasatinib, the second-generation tyrosine kinase inhibitor, has been considered a significant potential to overcome the ......
Safety and efficacy of dasatinib in patients with advanced gastrointestinal stromal tumors refractor
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Safety and efficacy of dasatinib in patients with advanced gastrointestinal stromal tumors refractor
目的 Dasatinib is a multi-target tyrosine kinase inhibitor which showed potentialanti-GIST activity in previous studies.......
A targeting liposomal structure by incorporating vincristine with dasatinib for treatment of invasiv
Recurrence of invasive breast cancer could arise from the residual cancer cells after comprehensive treatment.The residu......
In recent years,photodynamic therapy(PDT)has become an important cancer treatment technology.It has beenincreasingly use......
Dasatinib inhibits proliferation of liver cancer cells,but activation of Akt/mTOR compromises dasati
Dasatinib is a multi-target protein tyrosine kinase inhibitor.Due to its potent inhibition of Src,Abl,the platelet-deriv......
Dasatinib inhibits proliferation of liver cancer cells,but activation of Akt/mTOR compromises dasati
Dasatinib is a multi-target protein tyrosine kinase inhibitor.Due to its potent inhibition of Src,Abl,the platelet-deriv......
A sensitive, rapid, simple and economical ultra-performance liquid chromatography–tandem mass spectro-metric method (UP......
1例15岁慢性粒细胞白血病男性患儿因急变为急性淋巴细胞白血病合并中枢神经系统白血病给予达沙替尼50 mg口服，2次/d。用药1年后患儿......
1例11岁男性费城染色体阳性急性淋巴细胞性白血病患儿因伊马替尼耐药换用达沙替尼60 mg，1次/d口服。服药后约5 h，患儿出现全身肌肉、......
原发性骨髓纤维化(primary myelofibrosis,PMF)是一种慢性克隆性髓系疾病,特点是贫血、脾肿大、骨髓纤维化、骨硬化,可伴随发热、......
目的 合成2种聚乙二醇-达沙替尼结合物(JK120303和JK120304),并评价结合物JK120303和JK120304在K562人慢性髓系白血病皮下瘤模型中......
,Superiority of allogeneic hematopoietic stem cell transplantation to nilotinib and dasatinib for ad
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,Four-year follow-up of patients with imatinib-resistant or intolerant chronic myeloid leukemia rece
Dasatinib is a highly effective second-generation tyrosine kinase inhibitor used to treat chronic myeloid leukemia (CML)......
目的探讨达沙替尼导致肺动脉高压的临床特点和转归。方法回顾分析1例达沙替尼治疗过程中出现肺动脉高压患者的临床特点。以"达沙替......
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目的 观察接受酪氨酸激酶抑制剂( TKI)治疗的慢性髓系白血病(CML)患者的生育结果.方法 回顾性收集接受TKI治疗的CML患者或其配偶......
目的探讨慢性粒细胞白血病合并肺腺癌患者靶向药物治疗的药学监护要点。方法对1例服用达沙替尼和埃克替尼的慢性粒细胞白血病合并......
目的分析达沙替尼、尼洛替尼与伊马替尼对慢性髓系白血病(CML)慢性期患者的治疗效果。方法选取2012年8月至2015年8月收治的96例新......
1例53岁男性患者因职业性肿瘤(苯所致白血病)慢性粒细胞白血病使用达沙替尼片0.1 g,qd,用药9个月后出现心包积液,将“达沙替尼”用......
目的探讨伊马替尼和达沙替尼治疗初发慢性粒细胞白血病慢性期(CML-CP)的疗效。方法选择2010年1月至2016年6月郑州大学附属洛阳中心......
目的 探讨达沙替尼联合氟达拉滨对慢粒K562细胞的抑制作用.方法 选取慢粒K562细胞株进行研究,采用MTT法分别测定单独使用达沙替尼......
目的建立测定慢性粒细胞白血病（CML）患者血浆伊马替尼与达沙替尼浓度的HPLG-MS／MS法，并应用于临床治疗药物监测，为临床合理用药提供可靠......
目的 以壳聚糖、十八醇和羟丙甲基纤维素等辅料制备达沙替尼胃滞留剂,并对其体外释放性能进行考察.方法 利用正交实验、干法压片法......
Efficacy and Safety of Generic Dasatinib as a Second-line Treatment for Patients with Chronic Myeloi
Dasatinib is a second-generation tyrosine kinase inhibitor (TKI)and it could be used as a second-line treatment for pati......
目的：观察贞芪扶正颗粒联合达沙替尼治疗BCR-ABL阳性白血病的疗效和安全性。方法：40例BCR-ABL阳性慢性粒细胞白血病（CML）或PH阳性急性......
目的：探讨慢性髓系白血病（CML）使用达沙替尼治疗过程中导致相关乳糜胸的临床特征及转归。方法：收集我院3例达沙替尼治疗CML过程中导致......
本研究评价达沙替尼治疗原发或继发伊马替尼耐药的BCR/ABL阳性白血病的疗效和安全性。对27例原发或继发伊马替尼耐药的慢性髓系白......
慢性粒细胞白血病(CML)是一种获得性造血干细胞恶性克隆性疾病,占成人白血病的20%,酪氨酸激酶抑制剂(TKI)的出现开始了靶向治疗的......
Severe hemorrhagic colitis in a patient with chronic myeloid leukemia in the blastic phase after das
Dasatinib is a second-line tyrosine kinase inhibitor used in patients with imatinib resistant or intolerant chronic myel......
A 53-year-old man with chronic myeloid leukaemia developed significant hepatic dysfunction when treatment was changed fr......
A 53-year-old man with chronic myeloid leukaemia developed significant hepatic dysfunction when treatment was changed fr......
目的 探讨达沙替尼联合干扰素-α治疗慢性粒细胞白血病的临床疗效。方法 选取慢性髓细胞性白血病患者34例,根据治疗方法不同分为治......
A validated UPLC-MS/MS method for simultaneous determination of imatinib, dasatinib and nilotinib in
一个敏感、快速、简单、节俭的极端表演的液体层析双人脚踏车团度谱的方法(UPLC-MS/MS ) 作为内部标准用 gliquidone 在人的血浆为......
A validated UPLC-MS/MS method for simultaneous determination of imatinib, dasatinib and nilotinib in
一个敏感、快速、简单、节俭的极端表演的液体层析双人脚踏车团度谱的方法(UPLC-MS/MS ) 作为内部标准用 gliquidone 在人的血浆为......
目的建立GC法检测达沙替尼原料药中残留溶剂的方法。方法色谱柱为HP-DB624毛细管柱（30 mm×0.53 mm,3.0μm）,氢火焰离子化检测器......
Two Successful Successive Pregnancies in a Woman with CML Treated with Dasatinib and Temporary Peg-I
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目的:探讨达沙替尼(dasatinib)体外对人肾癌细胞系786-O及769-P增殖、凋亡及迁移的影响及其分子机制。方法:不同浓度(0~2μmol/L)......
回 回 产卜爹仇贱回——回 日E回。”。回祖 一回“。回干 肉果幻中 N_。NH lP7-ewwe--一”＄ MN。W;- __._——————》 砧叫]们......
目的：通过观察Btk抑制剂联合NFκB抑制剂及酪氨酸激酶Bcr-abl抑制剂,对B细胞肿瘤包括淋巴瘤细胞(Raji、Ramos)及急性淋巴细胞白血病......
目的考察小分子酪氨酸激酶抑制剂达沙替尼与吉非替尼的肝脏毒性,研究两者的肝脏毒性的作用机制,筛选寻找有效的肝脏保护剂,为两药......
1商品名:Sprycel 2开发与上市厂商本品由美国百时美施贵宝公司开发,于2006年2月首次在美国上市。3适应证本品适用于对包括甲磺酸伊......
达沙替尼(dasatinib),商品名为Sprycel,是由百时美施贵宝公司研发的一种口服的酪氨酸激酶抑制剂。该药于2006年6月28日通过美国FDA......
